Quote from Kyishi;1247412:
akali is the easiest way to win ascension. along with kat.
I don't think I have ever won a game in any mode that had an Akali in it. The akali always becomes extremely salty and accuses everyone else of not being any good at playing their role, even though everyone else is getting annoyed that the Akali is never where she should be.
Teemo is annoying to be up against though. He makes a mess of ascension because shrooms everywhere, which eventually wears down the ascended enough for it to be easy pickings.
I probably will run Heimerdinger again just because I had fun using him that one time. For now though it's back to Morgana and Soraka for me, I need to be somewhere betwen mage and healer.
When doing draft picks I usually try to ban the champs that I don't want to be up against unless someone on my team intends to use them. Who actually gets hit depends entirely on my mood and what I have had trouble with recently in that particular game mode.
Which for Ascension ended up being Paentheon, Katarina, Cassiopia, or Karthus.